WHY FERTILITY CONTROL?  
HISTORY  
THE IDEAL  
IMMUNO-
CONTRACEPTION
 
PZP VACCINE  
HOW MANY ANIMALS?  
ETHICAL ISSUES  
REGULATORY ISSUES  
APPLICATION  
THE FUTURE  
THE RESEARCH TEAM  
FUNDING  
OBTAINING PZP  
BIBLIOGRAPHY  
   
 

Future Research - Other Groups

Oral Contraceptives

Because of the need to inoculate animals twice the first year, and the difficulty of doing this with wild species, research is proceeding toward a "one-inoculation" vaccine. Such a vaccine would permit a single darting to cause one or more years of contraception. The approach under study incorporates the PZP into a non-toxic, bio-degradable material which can be formed into small pellets. The pellets can be designed to release the vaccine at predetermined times after injection (at one and three months currently) much the way time-release cold pills work. Initial trials were encouraging and continued trials are underway (see Eldridge et al. 1989).

Viral-Vectored Contraceptives

Researchers working with the Australian government are seeking to engineer the genes for PZP and similar contraceptive molecules into non-pathogenic viruses. These viruses could then be transmitted from animal to animal in wild populations. While there are some attractive features to this approach, the safety, environmental, and ethical issues associated with this technology will raise strong objections from the public and regulatory agencies in the U.S., and it probably will never be used here (see Robinson et al. 1997).

Abortifacients

At least two research groups are seeking to administer compounds which will cause abortion in the recipient animals. This has already been shown to be feasible in deer, but we are not pursuing this approach because of the social objections that will attend this method of wildlife control.