WHY FERTILITY CONTROL?  
HISTORY  
THE IDEAL  
IMMUNO-
CONTRACEPTION
 
PZP VACCINE  
HOW MANY ANIMALS?  
ETHICAL ISSUES  
REGULATORY ISSUES  
APPLICATION  
THE FUTURE  
THE RESEARCH TEAM  
FUNDING  
OBTAINING PZP  
BIBLIOGRAPHY  
   
 

A Brief History of Wildlife Fertility Control

The concept of wildlife fertility control is not new and research has been carried out for many years. Most of this work was based on the fruits of human contraceptive research and therefore mirrored human contraceptive technologies. This in turn meant that until recently, the most common approach to wildlife contraception was through the use of steroid hormones, and particularly natural and synthetic estrogens, progestins, and androgens, similar to those found or used in humans. Zoos really led the way, administering these compounds to captive animals, where delivery was not an issue, but their use in free-roaming wildlife was another issue. These compounds often worked in a pharmacological sense but they fell far short of the standards that permit them to be used with free-roaming wildlife. Basically, they failed because

1. they had to be given in extremely large quantities, ruling out remote delivery
2. they had to be administered too often
3. they caused a variety of pathologies in treated animals
4. the cost was relatively high
5. they often had profound effects upon social behaviors
6. they were often unsafe to administer to pregnant animals
7. they passed through the food chain to predators - human and otherwise - and scavengers.

Because of these shortcomings, there was little hope that they would ever be publicly-acceptable for use in free-roaming wildlife by regulatory agencies. For more extensive reading on the history of wildlife contraception we suggest Kirkpatrick and Turner, 1985, 1991, 1995; Seal 1991 (referenced in the Bibliography).